Get 25% off your first bottle when you subscribe!

Diagnostic Tools for Acid Reflux: Understanding GERD and LPR Testing

Reflux, while common, is multifaceted, presenting itself in various forms such as Gastroesophageal Reflux Disease (GERD) and Laryngopharyngeal Reflux (LPR). While these two forms may co-exist or overlap, they are distinct from each other.  Distinguishing between these conditions is crucial for accurate diagnosis and effective treatment. Diagnostic testing plays a pivotal role in guiding healthcare professionals, enabling tailored treatment strategies and preventing potential complications.

In this comprehensive guide, we’ll delve into the diagnostic testing procedures for GERD and LPR, shedding light on their significance in identifying and differentiating between these conditions. Whether you’re experiencing symptoms suggestive of acid reflux or seeking a deeper understanding of these disorders, this article aims to serve as a valuable resource in navigating the complexities of diagnosis and treatment.

Understanding GERD Diagnostic Testing

GERD, characterized by the reflux of stomach acid into the esophagus, necessitates a thorough diagnostic approach. Apart from the classic symptoms of heartburn and regurgitation, GERD can manifest in various other symptoms such as chest pain, chronic cough, and sore throat. Here are some key diagnostic tests for GERD:

Exploring LPR Diagnostic Testing

Diagnosing LPR, which primarily affects the throat and voice box, poses unique challenges due to its diverse range of symptoms, especially if classical heartburn is not present. Symptoms may include persistent sore throat, voice problems, coughing, throat clearing, and post-nasal drip. Here are some diagnostic tests for LPR:

Exploring Alternative Diagnostic Avenues

In the pursuit of less invasive diagnostic options, salivary testing emerges as a promising avenue. Tests like Peptest detect pepsin, an enzyme associated with reflux, offering a non-invasive alternative for LPR diagnosis. However, challenges persist in the clinical availability and utilization of salivary testing in the US, warranting further research and validation.

Patient-Reported Outcome Measures

Patient-Reported Outcome Measures (PROMs) such as the Reflux Symptom Index (RSI) and Reflux Symptoms Score (RSS) provide additional insights into LPR symptoms and laryngeal findings. Engaging with tools like the RSI or RSS  assessment can empower individuals to evaluate their symptoms and initiate meaningful discussions with healthcare providers.

> Take the RSS, here 


Diagnostic testing serves as the cornerstone of effective management in the realm of acid reflux disorders. These tests not only facilitate accurate diagnosis but also pave the way for personalized treatment strategies and improved patient outcomes. As you embark on your diagnostic journey, seeking guidance from trusted healthcare providers for comprehensive evaluations and tailored treatment plans is paramount. 

An occasional episode of heartburn may be normal, but if you’re experiencing heartburn several times a week, it may be time to consult your doctor. We created this worksheet for you to download and print, which will help you prepare for your appointment.

For further insights into LPR diagnosis and treatment, tune in to the BackTable ENT Podcast featuring our VP of Education, Dr. Inna Husain, where she discusses diagnosis, treatment, and multidisciplinary care of patients with LPR.